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Cytotoxicity of γ-Mangostin (γ-Mag) in BMMs (A) Chemical structure of γ-Mag. (B) Viability of BMMs treated with increasing concentrations of γ-Mag for 48 h, assessed by MTS assay. (C) Viability of BMMs treated with 4 μM γ-Mag over time, measured by MTS assay. Data are presented as mean ± S.E.M. from three independent experiments, each performed with six replicates per group (n = 6). * P < 0.05, ** P < 0.01 compared to the 0 μM group. One-way ANOVA followed by Tukey’s post hoc test was used for statistical analysis. OD, optical density; <t>M-CSF,</t> macrophage colony-stimulating factor; γ-Mag, γ-Mangostin; BMMs, bone marrow-derived macrophages; MTS, multiple tumor suppressor.
Recombinant Rat M Csf, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cytotoxicity of γ-Mangostin (γ-Mag) in BMMs (A) Chemical structure of γ-Mag. (B) Viability of BMMs treated with increasing concentrations of γ-Mag for 48 h, assessed by MTS assay. (C) Viability of BMMs treated with 4 μM γ-Mag over time, measured by MTS assay. Data are presented as mean ± S.E.M. from three independent experiments, each performed with six replicates per group (n = 6). * P < 0.05, ** P < 0.01 compared to the 0 μM group. One-way ANOVA followed by Tukey’s post hoc test was used for statistical analysis. OD, optical density; <t>M-CSF,</t> macrophage colony-stimulating factor; γ-Mag, γ-Mangostin; BMMs, bone marrow-derived macrophages; MTS, multiple tumor suppressor.
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Cytotoxicity of γ-Mangostin (γ-Mag) in BMMs (A) Chemical structure of γ-Mag. (B) Viability of BMMs treated with increasing concentrations of γ-Mag for 48 h, assessed by MTS assay. (C) Viability of BMMs treated with 4 μM γ-Mag over time, measured by MTS assay. Data are presented as mean ± S.E.M. from three independent experiments, each performed with six replicates per group (n = 6). * P < 0.05, ** P < 0.01 compared to the 0 μM group. One-way ANOVA followed by Tukey’s post hoc test was used for statistical analysis. OD, optical density; <t>M-CSF,</t> macrophage colony-stimulating factor; γ-Mag, γ-Mangostin; BMMs, bone marrow-derived macrophages; MTS, multiple tumor suppressor.
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MedChemExpress m csf
Cytotoxicity of γ-Mangostin (γ-Mag) in BMMs (A) Chemical structure of γ-Mag. (B) Viability of BMMs treated with increasing concentrations of γ-Mag for 48 h, assessed by MTS assay. (C) Viability of BMMs treated with 4 μM γ-Mag over time, measured by MTS assay. Data are presented as mean ± S.E.M. from three independent experiments, each performed with six replicates per group (n = 6). * P < 0.05, ** P < 0.01 compared to the 0 μM group. One-way ANOVA followed by Tukey’s post hoc test was used for statistical analysis. OD, optical density; <t>M-CSF,</t> macrophage colony-stimulating factor; γ-Mag, γ-Mangostin; BMMs, bone marrow-derived macrophages; MTS, multiple tumor suppressor.
M Csf, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Sino Biological recombinant mouse m csf
Cytotoxicity of γ-Mangostin (γ-Mag) in BMMs (A) Chemical structure of γ-Mag. (B) Viability of BMMs treated with increasing concentrations of γ-Mag for 48 h, assessed by MTS assay. (C) Viability of BMMs treated with 4 μM γ-Mag over time, measured by MTS assay. Data are presented as mean ± S.E.M. from three independent experiments, each performed with six replicates per group (n = 6). * P < 0.05, ** P < 0.01 compared to the 0 μM group. One-way ANOVA followed by Tukey’s post hoc test was used for statistical analysis. OD, optical density; <t>M-CSF,</t> macrophage colony-stimulating factor; γ-Mag, γ-Mangostin; BMMs, bone marrow-derived macrophages; MTS, multiple tumor suppressor.
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Sino Biological recombinant macrophage colony
Cytotoxicity of γ-Mangostin (γ-Mag) in BMMs (A) Chemical structure of γ-Mag. (B) Viability of BMMs treated with increasing concentrations of γ-Mag for 48 h, assessed by MTS assay. (C) Viability of BMMs treated with 4 μM γ-Mag over time, measured by MTS assay. Data are presented as mean ± S.E.M. from three independent experiments, each performed with six replicates per group (n = 6). * P < 0.05, ** P < 0.01 compared to the 0 μM group. One-way ANOVA followed by Tukey’s post hoc test was used for statistical analysis. OD, optical density; <t>M-CSF,</t> macrophage colony-stimulating factor; γ-Mag, γ-Mangostin; BMMs, bone marrow-derived macrophages; MTS, multiple tumor suppressor.
Recombinant Macrophage Colony, supplied by Sino Biological, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Sino Biological recombinant macrophage colony stimulating factor
Cytotoxicity of γ-Mangostin (γ-Mag) in BMMs (A) Chemical structure of γ-Mag. (B) Viability of BMMs treated with increasing concentrations of γ-Mag for 48 h, assessed by MTS assay. (C) Viability of BMMs treated with 4 μM γ-Mag over time, measured by MTS assay. Data are presented as mean ± S.E.M. from three independent experiments, each performed with six replicates per group (n = 6). * P < 0.05, ** P < 0.01 compared to the 0 μM group. One-way ANOVA followed by Tukey’s post hoc test was used for statistical analysis. OD, optical density; <t>M-CSF,</t> macrophage colony-stimulating factor; γ-Mag, γ-Mangostin; BMMs, bone marrow-derived macrophages; MTS, multiple tumor suppressor.
Recombinant Macrophage Colony Stimulating Factor, supplied by Sino Biological, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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MedChemExpress factor m csf
Cytotoxicity of γ-Mangostin (γ-Mag) in BMMs (A) Chemical structure of γ-Mag. (B) Viability of BMMs treated with increasing concentrations of γ-Mag for 48 h, assessed by MTS assay. (C) Viability of BMMs treated with 4 μM γ-Mag over time, measured by MTS assay. Data are presented as mean ± S.E.M. from three independent experiments, each performed with six replicates per group (n = 6). * P < 0.05, ** P < 0.01 compared to the 0 μM group. One-way ANOVA followed by Tukey’s post hoc test was used for statistical analysis. OD, optical density; <t>M-CSF,</t> macrophage colony-stimulating factor; γ-Mag, γ-Mangostin; BMMs, bone marrow-derived macrophages; MTS, multiple tumor suppressor.
Factor M Csf, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Cytotoxicity of γ-Mangostin (γ-Mag) in BMMs (A) Chemical structure of γ-Mag. (B) Viability of BMMs treated with increasing concentrations of γ-Mag for 48 h, assessed by MTS assay. (C) Viability of BMMs treated with 4 μM γ-Mag over time, measured by MTS assay. Data are presented as mean ± S.E.M. from three independent experiments, each performed with six replicates per group (n = 6). * P < 0.05, ** P < 0.01 compared to the 0 μM group. One-way ANOVA followed by Tukey’s post hoc test was used for statistical analysis. OD, optical density; M-CSF, macrophage colony-stimulating factor; γ-Mag, γ-Mangostin; BMMs, bone marrow-derived macrophages; MTS, multiple tumor suppressor.

Journal: Frontiers in Pharmacology

Article Title: γ-Mangostin attenuates osteoclastogenesis and bone resorption by suppressing the PI3K/AKT/NF-κB pathway

doi: 10.3389/fphar.2025.1742401

Figure Lengend Snippet: Cytotoxicity of γ-Mangostin (γ-Mag) in BMMs (A) Chemical structure of γ-Mag. (B) Viability of BMMs treated with increasing concentrations of γ-Mag for 48 h, assessed by MTS assay. (C) Viability of BMMs treated with 4 μM γ-Mag over time, measured by MTS assay. Data are presented as mean ± S.E.M. from three independent experiments, each performed with six replicates per group (n = 6). * P < 0.05, ** P < 0.01 compared to the 0 μM group. One-way ANOVA followed by Tukey’s post hoc test was used for statistical analysis. OD, optical density; M-CSF, macrophage colony-stimulating factor; γ-Mag, γ-Mangostin; BMMs, bone marrow-derived macrophages; MTS, multiple tumor suppressor.

Article Snippet: Recombinant rat M-CSF (Catalog #: HY-P7247, lot #: 508608) and RANKL (Catalog #: 9366-TN-025, lot #: DEIZ0322121) were purchased respectively from Medchemexpress Corporation and R&D Systems (United States). α-MEM medium, fetal bovine serum (FBS), and penicillin-streptomycin solution were purchased from Gibco (United States).

Techniques: MTS Assay, Derivative Assay